First-line TB drugs achieve only very minimal concentrations in breast milk and toxicity to infants has not been reported. TB transmission via breast milk has not been reported in the chemotherapeutic era.176
Good practice statements
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Breastfeeding is to be encouraged in women taking first-line TB therapy.
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Pyridoxine supplementation for the breastfeeding infant is not necessary unless the infant is also taking isoniazid.
See Chapter 9: Pediatric Tuberculosis for management of the neonate and peripartum periods.
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