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Investigation and treatment of symptoms and signs of severe or life-threatening TB disease (eg, life-threatening hemoptysis, cachexia/malnutrition)
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Severe and morbid forms of TB, such as TB meningitis, cerebral TB, TB pericarditis
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Establishment of an acceptable drug regimen in patients with significant/severe drug-related adverse events or known/suspected multidrug-resistant disease
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Drug desensitization
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Management of co-morbid medical conditions whether related or unrelated to TB diagnosis (eg, heart failure, respiratory failure or recent solid organ transplantation)
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Institution of airborne isolation if this cannot be achieved in the outpatient setting
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Involuntary admission when all other measures are unsuccessful (should be an extremely rare event and performed as a last resort in consultation with public health authorities)
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